Avoid or Use Alternate Drug.Įsmolol and timolol both increase anti-hypertensive channel blocking. Additive bradycardia effect may result in syncope.Įsmolol and sotalol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.Įsmolol increases toxicity of rivastigmine by pharmacodynamic synergism. Avoid or Use Alternate Drug.Įsmolol and propranolol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.Įsmolol and pindolol both increase anti-hypertensive channel blocking. ![]() Avoid or Use Alternate Drug.Įsmolol and penbutolol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.Įsmolol and nebivolol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.Įsmolol and nadolol both increase anti-hypertensive channel blocking. Expect additive negative inotropic effects of mavacamten and other drugs that reduce cardiac contractility.Įsmolol and metoprolol both increase anti-hypertensive channel blocking. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension.Įither increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug.Įither increases effects of the other by pharmacodynamic synergism. Avoid coadministration of fexinidazole with drugs known to induce bradycardia.Įsmolol and labetalol both increase anti-hypertensive channel blocking. Can increase risk of bradycardia.Įither increases effects of the other by pharmacodynamic synergism. Can increase risk of bradycardia.Įither decreases toxicity of the other by unspecified interaction mechanism. Avoid or Use Alternate Drug.Įither increases toxicity of the other by unspecified interaction mechanism. Avoid or Use Alternate Drug.Ĭeliprolol and esmolol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.Ĭarvedilol and esmolol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.īisoprolol and esmolol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.īetaxolol and esmolol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug.Ītenolol and esmolol both increase anti-hypertensive channel blocking. 2nd loading dose of 0.5 mg/kg/min for 1 min, THENĪcebutolol and esmolol both increase anti-hypertensive channel blocking. Initial bolus: 80 mg (~1 mg/kg) IVP over 30 sec, THEN May repeat loading dose or increase infusion up to 0.3 mg/kg/min if necessary Intraoperative tachycardia/hypertension Higher maintenance doses may be required, up to 0.25-0.3 mg/kg/min Hypertensive emergency If HR/BP not controlled after 5 min, repeat bolus (ie, 0.5 mg/kg/min for 1 min), then initiate infusion of 0.1 mg/kg/min IV Shown to decrease mortality in hypertension and post-myocardial infarction Other Indications & UsesĢ.5 mg PO qDay increase dose gradually Supraventricular tachycardia ![]() Less effective than thiazide diuretics in black and geriatric patients Not necessary to supplement dose not dialyzable Additional Information May repeat loading dose or increase infusion up to 0.3 mg/kg/min if necessary Renal Impairment Higher maintenance doses may be required, up to 0.25-0.3 mg/kg/min Hypertensive Emergency May administer a 3rd bolus if needed, then a maintenance infusion of 0.15 mg/kg/min IV If HR/BP not controlled after 5 min, repeat bolus (ie, 500 mcg/kg/min for 1 min), then initiate infusion of 0.1 mg/kg/min IV Maintenance: Start 0.05 mg/kg/min IV for 4 min, may increase by 0.05 mg/kg up to 0.2 mg/kg/min
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